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毕国强  教授



Name:  Bi Guo-Qiang (毕国强)
Born:    November 1967, Hebei, P.R. China
Address: School of Life Sciences
University of Science and Technology of China
230026 Hefei, P. R. China
Tel: 86-551-63602466
E-mail: gqbi@ustc.edu.cn
 
EDUCATION AND RESEARCH EXPERIENCE
 1985-1989 B.S. (Physics), Beijing University, China
 1990-1991 M.S. (Physics), New York University, USA
 1991-1996 Ph.D. (Biophysics), University of California, Berkeley, USA
 1996-2000 Postdoctoral Fellow, University of California, San Diego, USA
 2000-2009 Assistant Professor, Associate Professor (with tenure), University of Pittsburgh School of Medicine, USA
 2007- Professor, University of Science and Technology of China
 2014- Senior Investigator, CAS Center for Excellence in Brain Research
 
RESEARCH INTERESTS
1) Synaptic structure and plasticity
2) Neural circuitstructure and dynamics
3) Learning, memory and related brain diseases
4) Ultra-high resolution optical and electron imaging
 
CURRENT RESEARCH PROJECTS
1) National Outstanding Young Scientist Award, National Natural Science Foundation of China (2007-2011)
2) Dynamic Assembly of Protein Complex, Ministry of Science and Technology of China (2007-2012)
 
REPRESENTATIVE PUBLICATIONS
1) Shim SH, Xia C, Zhong G, Babcock HP, Vaughan JC, Huang B, Wang X, Xu C, Bi GQ* & Zhuang X*, Super-resolution fluorescence imaging of organelles in live cells with photoswitchable membrane probes. Proc Natl Acad Sci U S A 109: 13978-13983 (2012).
2) Zhang JC, Lau PM & Bi GQ*, Gain in sensitivity and loss in temporal contrast of STDP by dopaminergic modulation at hippocampal synapses. Proc Natl Acad Sci U S A 106: 13028-13033 (2009).
3) Lau, PM & Bi, GQ*, Synaptic mechanisms of persistent reverberatory activity in neuronal networks. Proc Natl Acad Sci U S A 102: 10333-10338 (2005).
4) Bi, GQ*& Rubin, J Timing in synaptic plasticity: from detection to integration. Trends Neurosci 28: 222-228 (2005).
5) Wang HX, Gerkin, RC, Nauen, DW& Bi, GQ*,Coactivation and timing-dependent integration of synaptic potentiation and depression. Nat Neurosci 8: 187-193 (2005).
6) Bi, GQ*& Poo, MM*, Synaptic modifications by correlated activity: Hebb's postulate revisited. Ann Rev Neurosci 24: 139-166 (2001).
7) Bi, GQ*& Poo, MM, Distributed synaptic modification in neural networks induced by patterned stimulation. Nature 401: 792-796 (1999).
8) Bi, GQ & Poo, MM,Synaptic modifications in cultured hippocampal neurons: Dependence on spike timing, synaptic strength, and postsynaptic cell type. J Neurosci 18: 10464-10472 (1998).
9) Steinhardt, RA,Bi, GQ &AldertonJM, Cell membrane resealing by a vesicular mechanism similar to neurotransmitter release. Science 263: 390-393 (1994)


 

 


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